Plasma metabolomics revealed an increase in a number of amino acids in response to MC intake, but not placebo. There was also a treatment effect for higher alertness (mean difference: 5♹, 95 % CI: 1♳, 10♵ %) and lower mental fatigue ratings (mean difference -9♵, 95 % CI: -16♵, -2♵ %) with MC. The large shining red fruit ripens around late June and is one of the finest sour cherries on the market. This variety is self-fruiting, but cross-pollination can increase the fruit production of this already heavy bearer. After 3 months, the MC resulted in higher accuracy in digit vigilance (mean difference: 3♳, 95 % CI: 0♲, 6♴ %) with lower number of false alarms (mean difference: -1♲, 95 % CI: -2♰, -0♴) compared with the placebo. Montmorency Cherry has been crossed with Prunus tomentosa. Cerebral blood flow was also monitored by near-infrared spectroscopy during the task battery, and questionnaires were administered to determine subjective sleep and health status and plasma metabolomics were analysed before and after supplementation. Cognitive function and mood were assessed before and after supplementation using a computerised cognitive task battery and visual analogue scales. In a 3-month double-blinded, placebo-controlled parallel study, middle-aged adults (mean ± sd: 48 ± 6 years) were randomly assigned to either 30 ml twice daily of MC (n 25) or the same amount of an isoenergetic placebo (n 25). The current study aimed to determine the influence of chronic MC supplementation on cognitive function and mood. Tart Montmorency cherries (MC) are a particularly rich source of anthocyanins and other polyphenols that have been shown to elicit antioxidant, anti-inflammatory and vasomodulatory actions.
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